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ICAM3/CD50 Rekombinanter Antikörper

ICAM3/CD50 Rekombinant Antikörper für IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241418C10

Kat-Nr. : 84335-3-PBS

Synonyme

CDW50, ICAM3, 241418C10, CD50, ICAM 3

Filter:
  • Immunofluorescence (IF) / fluorescent staining of Ramos cells using ICAM3/CD50 Recombinant antibody (84335-3-RR)

    IF Staining of Ramos using 84335-3-RR (same clone as 84335-3-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Ramos cells using ICAM3 antibody (84335-3-RR, Clone: 241418C10 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84335-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84335-3-RR

    Affinity and Kinetic Characterization of 84335-3-RR

    Biolayer interferometry (BLl) kinetic assays of 84335-3-RR against Human ICAM3/CD50 were performed. The affinity constant is 1.45 nM.

Geprüfte Anwendungen

Produktinformation

84335-3-PBS bindet in IF/ICC, Indirect ELISA ICAM3/CD50 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name intercellular adhesion molecule 3
Berechnetes Molekulargewicht 547 aa, 60 kDa
GenBank-ZugangsnummerBC058903
Gene symbol ICAM3/CD50
Gene ID (NCBI) 3385
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Intercellular Adhesion Molecule 3 (ICAM-3), also known as CD50, is a member of the immunoglobulin superfamily. It is a transmembrane glycoprotein that contains an N-terminus extracellular domain, a single transmembrane domain, and a C-terminus cytoplasmic domain. ICAM-3 possesses 2-9 Ig-like C2-type domains in its extracellular region and is known to bind to the leukocyte adhesion protein LFA-1 . This molecule is expressed on leukocytes and epidermal Langerhans cells and plays a significant role in immune cell interactions and T lymphocyte activation.