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ICAM5 Polyklonaler Antikörper

ICAM5 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12759-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse brain tissue using ICAM5 Polyclonal antibody (12759-1-AP)

    WB analysis of mouse brain using 12759-1-AP (same clone as 12759-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 12759-1-AP (ICAM5 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12759-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse brain tissue using ICAM5 Polyclonal antibody (12759-1-AP)

    WB analysis of mouse brain using 12759-1-AP (same clone as 12759-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 12759-1-AP (ICAM5 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12759-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

12759-1-PBS bindet in WB, Indirect ELISA ICAM5 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ICAM5 fusion protein Ag3303
Vollständiger Name intercellular adhesion molecule 5, telencephalin
Berechnetes Molekulargewicht 924 aa, 97 kDa
Beobachtetes Molekulargewicht 140 kDa
GenBank-ZugangsnummerBC026338
Gene symbol ICAM5
Gene ID (NCBI) 7087
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ICAM-5, also known as telencephalin, is a type I integral membrane glycoprotein of the immunoglobulin superfamily. It is specifically expressed in the postnatal excitatory neuronal cell bodies, dendritic shafts, and dendritic filopodia of the telencephalon. ICAM-5 functions in both the immune and nervous systems. ICAM-5 strongly stimulates neurite outgrowth. It is cleaved by matrix metalloproteases upon activation of glutamate receptors or degraded through endocytosis resulting in increased spine maturation. The cleaved soluble fragment of ICAM-5 is immunosuppressive, which may be important in neuronal inflammatory diseases. (PMID: 10402269; 17682049; 25300135)