ICAM5 Rekombinanter Antikörper

ICAM5 Rekombinant Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus, Ratte

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

243100H5

Kat-Nr. : 85941-1-PBS

Synonyme

Icam3, ICAM-5, Intercellular adhesion molecule 5, Telencephalin, Tlcn

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  WB analysis using 85941-1-RR (same clone as 85941-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85941-1-RR (Icam5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85941-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 85941-1-RR (same clone as 85941-1-PBS)

  IP result of anti-ICAM5 (IP:85941-1-RR, 4ug; Detection:85941-1-RR 1:4000) with mouse brain tissue lysate 2120 ug. This data was developed using the same antibody clone with 85941-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

85941-1-PBS bindet in WB, IP, Indirect ELISA ICAM5 und zeigt Reaktivität mit Maus, Ratten

• Getestete Reaktivität: Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: ICAM5 fusion protein Eg2868
• Vollständiger Name: intercellular adhesion molecule 5, telencephalin
• Berechnetes Molekulargewicht: 97 kDa
• Beobachtetes Molekulargewicht: 150 kDa
• GenBank-Zugangsnummer: N/A
• Gene symbol: Icam5
• Gene ID (NCBI): 15898
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ICAM-5, also known as telencephalin, is a type I integral membrane glycoprotein of the immunoglobulin superfamily. It is specifically expressed in the postnatal excitatory neuronal cell bodies, dendritic shafts, and dendritic filopodia of the telencephalon. ICAM-5 functions in both the immune and nervous systems. ICAM-5 strongly stimulates neurite outgrowth. It is cleaved by matrix metalloproteases upon activation of glutamate receptors or degraded through endocytosis resulting in increased spine maturation. The cleaved soluble fragment of ICAM-5 is immunosuppressive, which may be important in neuronal inflammatory diseases. (PMID: 10402269; 17682049; 25300135)