IDH1 Rekombinanter Antikörper
IDH1 Rekombinant Antikörper für WB, IHC, FC (Intra), Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, IHC, FC (Intra), Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
6L18
Kat-Nr. : 81176-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
81176-1-PBS bindet in WB, IHC, FC (Intra), Indirect ELISA IDH1 und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Rekombinant |
| Typ | Antikörper |
| Immunogen | IDH1 fusion protein Ag19749 |
| Vollständiger Name | isocitrate dehydrogenase 1 (NADP+), soluble |
| Berechnetes Molekulargewicht | 414 aa, 47 kDa |
| Beobachtetes Molekulargewicht | 46 kDa |
| GenBank-Zugangsnummer | BC012846 |
| Gene symbol | IDH1 |
| Gene ID (NCBI) | 3417 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer(PMID:15173171). IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25% each wild type and mutant homo-dimers and 50% hetero-dimers present in the tumor cells(PMID:21079649 ).









