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IDS Polyklonaler Antikörper

IDS Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29375-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using IDS Polyclonal antibody (29375-1-AP)

    WB analysis using 29375-1-AP (same clone as 29375-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29375-1-AP (IDS antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29375-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

29375-1-PBS bindet in WB, Indirect ELISA IDS und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen IDS fusion protein Ag31132
Vollständiger Name iduronate 2-sulfatase
Berechnetes Molekulargewicht312aa,35 kDa; 550aa,62 kDa
Beobachtetes Molekulargewicht65-72 kDa
GenBank-ZugangsnummerBC006170
Gene symbol IDS
Gene ID (NCBI) 3423
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181).