IFIT3 Monoklonaler Antikörper
IFIT3 Monoklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA
Wirt / Isotyp
Maus / IgG2a
Getestete Reaktivität
human
Anwendung
WB, IHC, IF/ICC, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
2C8B10
Kat-Nr. : 67208-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
67208-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA IFIT3 und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Maus / IgG2a |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | IFIT3 fusion protein Ag7518 |
Vollständiger Name | IFIT3 |
Berechnetes Molekulargewicht | 56 kDa |
Beobachtetes Molekulargewicht | 60 kDa |
GenBank-Zugangsnummer | BC004977 |
Gene symbol | IFIT3 |
Gene ID (NCBI) | 3437 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
IFIT3 (IFN-induced protein with tetratricopeptide repeats 3), also known as IFIT-4, ISG-60 or RIG-G, is a 56 kDa IFN induced protein. IFIT3 has been identified to be associated with strong IFN antiviral activity. Upon RNA virus infection, IFIT3 is significantly induced, ectopic expression or knockdown of IFIT3 could, respectively, enhance or impair IFN regulatory factor 3 (IRF3)-mediated gene expression. IFIT3 thus may serve as an important modulator in innate immunity, revealing a new function of the IFIT family proteins.