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IFITM2-Specific Monoklonaler Antikörper

IFITM2-Specific Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3D5F7

Kat-Nr. : 66137-1-PBS

Synonyme

IFITM2, 1 8D, 18D, 3D5F7, DSPA2c

Filter:
  • Western Blot (WB) analysis of HepG2 cells using IFITM2-Specific Monoclonal antibody (66137-1-Ig)

    WB analysis of HepG2 using 66137-1-Ig (same clone as 66137-1-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 66137-1-Ig (IFITM2-specific antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66137-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of recombinant protein using IFITM2-Specific Monoclonal antibody (66137-1-Ig)

    WB analysis of recombinant protein using 66137-1-Ig (same clone as 66137-1-PBS)

    IFITM1 (Lane 1), IFITM2 (Lane 2) and IFITM3 (Lane 3) fusion proteins (20ng/lane) were subjected to SDS-PAGE followed by western blot with IFITM2 monoclonal antibody (66137-1-Ig) at dilution of 1:10,000. This data was developed using the same antibody clone with 66137-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HepG2 cells using IFITM2-Specific Monoclonal antibody (66137-1-Ig)

    WB analysis of HepG2 using 66137-1-Ig (same clone as 66137-1-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 66137-1-Ig (IFITM2-specific antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66137-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of MCF-7 cells using IFITM2-Specific Monoclonal antibody (66137-1-Ig)

    WB analysis of MCF-7 using 66137-1-Ig (same clone as 66137-1-PBS)

    MCF7 cells were subjected to SDS PAGE followed by western blot with 66137-1-Ig (IFITM2-specific antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66137-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

66137-1-PBS bindet in WB, Indirect ELISA IFITM2-Specific und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name interferon induced transmembrane protein 2 (1-8D)
Beobachtetes Molekulargewicht 15 kDa
GenBank-ZugangsnummerNM_006435
Gene symbol IFITM2
Gene ID (NCBI) 10581
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IFITM2, also named as 1-8D, belongs to the CD225 family. It is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. IFITM2 induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. It is overexpressed in colon carcinoma. IFITM2 is a novel pro-apoptotic gene that will provide new insights into the regulated cellular pathways to death.(PMID:19544527) This antibody is specific to IFTIM2.