IFN Alpha Monoklonaler Antikörper
IFN Alpha Monoklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Maus / IgG2a
Getestete Reaktivität
human
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
4A2A11
Kat-Nr. : 66162-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
66162-1-PBS bindet in WB, Indirect ELISA IFN Alpha und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Maus / IgG2a |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | IFN Alpha fusion protein Ag12533 |
Vollständiger Name | IFNA1 |
Berechnetes Molekulargewicht | 189 aa, 22 kDa |
Beobachtetes Molekulargewicht | 22 kDa |
GenBank-Zugangsnummer | BC074928 |
Gene symbol | IFN alpha1 |
Gene ID (NCBI) | 3439 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
IFNA1 (IF-alpha) is a member of the Type I IFN (1) family best known for their antiviral activity. It is a key cytokine regulating the activity of B cells, T-helper cells (Th cells), cDCs and natural killer cells (NK cells). IFNA1 induces B cell maturation into plasma cells and immunoglobulin production. IFNA1 plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). IFNA1 was the first cytokine to show clinical benefit in the treatment of certain types of cancer, including melanoma, chronic myelogenous leukemia, and renal cancer.