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IFN-alpha 4/IFNA4 Polyklonaler Antikörper

IFN-alpha 4/IFNA4 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33237-1-PBS

Synonyme

IFNA4, IFN-alpha 4, IFN-alpha-4, IFN-α4 , Interferon alpha 4

Filter:
  • Western Blot (WB) analysis of various lysates using IFN-alpha 4/IFNA4 Polyclonal antibody (33237-1-AP)

    WB analysis using 33237-1-AP (same clone as 33237-1-PBS)

    Human IFN-alpha 4 recombinant protein (Cat No.Eg4962) was subjected to SDS PAGE, followed by western blot with 33237-1-AP (IFN-alpha 4/IFNA4 antibody) at a dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33237-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

33237-1-PBS bindet in WB, Indirect ELISA IFN-alpha 4/IFNA4 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen IFN-alpha 4/IFNA4 fusion protein Eg4962
Vollständiger Name interferon, alpha 4
GenBank-ZugangsnummerBC113642
Gene symbol IFNA4
Gene ID (NCBI) 3441
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IFN-alpha 4 (IFN-α4 or IFNA4) belongs to the type I interferon family, a group of cytokines primarily produced in response to viral infections. As a key player in the innate immune response, IFN-α4 provides the body's first line of defense against pathogens by inducing an antiviral state in neighboring cells. Produced primarily by macrophages, IFN-α4 exerts its antiviral effects by binding to the interferon alpha receptor (IFNAR) on cell surfaces, thereby activating downstream immune signaling pathways . This binding triggers the expression of antiviral proteins, such as a protein kinase and an oligoadenylate synthetase, which inhibit viral RNA replication and enhance natural killer cell cytotoxicity against viruses.