IFN Alpha Polyklonaler Antikörper

IFN Alpha Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human und mehr (1)

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(17)

Kat-Nr. : 18013-1-AP

Synonyme

IFL, IFN, IFN ALPHA, IFN alpha 1/13, IFNA@, IFNA1, IFNA13, IFN-alpha, Interferon alpha 1/13, Interferon alpha D, interferon, alpha 1, Interferon-α1, LeIF D

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  WB analysis of Recombinant protein using 18013-1-AP

  Recombinant protein were subjected to SDS PAGE followed by western blot with 18013-1-AP (Interferon alpha antibody at dilution of 1:3000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Recombinant protein

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 8 publications below
• IHC: See 10 publications below
• IF: See 2 publications below

Produktinformation

18013-1-AP bindet in WB, IHC, IF, ELISA IFN Alpha und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: IFN Alpha fusion protein Ag12533
• Vollständiger Name: IFNA1
• Berechnetes Molekulargewicht: 189 aa, 22 kDa
• GenBank-Zugangsnummer: BC074928
• Gene symbol: IFN alpha1
• Gene ID (NCBI): 3439
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IFNA1 (IFN-alpha) is a member of the Type I IFN (1) family best known for their antiviral activity. It is a key cytokine regulating the activity of B cells, T-helper cells (Th cells), cDCs and natural killer cells (NK cells). IFN-alpha induces B cell maturation into plasma cells and immunoglobulin production. IFN-alpha plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). IFN-alpha was the first cytokine to show clinical benefit in the treatment of certain types of cancer, including melanoma, chronic myelogenous leukemia, and renal cancer.

Publikationen

Species	Application	Title
human	IHC	J Immunother Cancer; Helicobacter pylori infection disturbs the tumor immune microenvironment and is associated with a discrepant prognosis in gastric de novo diffuse large B-cell lymphoma.; Authors - Yuwei Deng
human,mouse	IHC	Cell Death Dis; Enhancing immunotherapy efficacy in colorectal cancer: targeting the FGR-AKT-SP1-DKK1 axis with DCC-2036 (Rebastinib); Authors - Xiguang Chen
human,mouse	WB,IHC	Oncogene; Reciprocal regulation between ferroptosis and STING-type I interferon pathway suppresses head and neck squamous cell carcinoma growth through dendritic cell maturation; Authors - Mingyu Li
human		mBio; Early enterovirus translation deficits extend viral RNA replication and elicit sustained MDA5-directed innate signaling; Authors - Mikhail I Dobrikov
human	IF	Ann Allergy Asthma Immunol; Lower viral loads in subjects with rhinovirus-challenged allergy despite reduced innate immunity.; Authors - Xin Feng
mouse	IHC	Immunol Lett; Acute Effects of TLR3 agonist Poly(I:C) on Bone Marrow Hematopoietic Progenitor Cells in Mice; Authors - Xin Shu