• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

IFNAR1 Rekombinanter Antikörper

IFNAR1 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

230549B1

Kat-Nr. : 98067-1-PBS

Synonyme

IFN alpha REC, Cytokine receptor class-II member 1, CRF2-1, CRF2 1, AVP

Filter:
  • Flow cytometry (FC) experiment of U-937 cells using Anti-Human IFNAR1 Rabbit Recombinant Antibody (98067-1-RR)

    FC experiment of U-937 using 98067-1-RR (same clone as 98067-1-PBS)

    1x10^6 U-937 cells were surface stained with 0.25 ug Anti-Human IFNAR1 Rabbit Recombinant Antibody (98067-1-RR, Clone:230549B1) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were not fixed. This data was developed using the same antibody clone with 98067-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98067-1-RR

    Affinity and Kinetic Characterization of 98067-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98067-1-RR against Human IFNAR1 were performed. The affinity constant is 1.15 nM.

Geprüfte Anwendungen

Produktinformation

98067-1-PBS bindet in FC IFNAR1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name interferon (alpha, beta and omega) receptor 1
Berechnetes Molekulargewicht 557 aa, 64 kDa
GenBank-ZugangsnummerBC021825
Gene symbol IFNAR1
Gene ID (NCBI) 3454
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C.

Hintergrundinformationen

Interferon alpha and beta receptor subunit 1 (IFNAR1) is a type I membrane protein that associates with IFNAR2 to form the receptor for type I interferons, including interferons-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2, and then increase transcription of the IFN-induced genes whose products exert antiviral, immunomodulatory, and antiproliferative effects.