IFNAR1 Rekombinanter Antikörper

IFNAR1 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

230549B1

Kat-Nr. : 98067-1-RR

Synonyme

IFN alpha REC, Cytokine receptor class-II member 1, CRF2-1, CRF2 1, AVP

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  FC experiment of U-937 using 98067-1-RR

  1x10^6 U-937 cells were surface stained with 0.25 ug Anti-Human IFNAR1 Rabbit Recombinant Antibody (98067-1-RR, Clone:230549B1) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)(red), or 0.25 ug Isotype Control (blue). Cells were not fixed.

• 

  Affinity and Kinetic Characterization of 98067-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98067-1-RR against Human IFNAR1 were performed. The affinity constant is 1.15 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: U-937-Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98067-1-RR bindet in FC IFNAR1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: interferon (alpha, beta and omega) receptor 1
• Berechnetes Molekulargewicht: 557 aa, 64 kDa
• GenBank-Zugangsnummer: BC021825
• Gene symbol: IFNAR1
• Gene ID (NCBI): 3454
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

Interferon alpha and beta receptor subunit 1 (IFNAR1) is a type I membrane protein that associates with IFNAR2 to form the receptor for type I interferons, including interferons-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2, and then increase transcription of the IFN-induced genes whose products exert antiviral, immunomodulatory, and antiproliferative effects.