IFNGR1/CD119 Monoklonaler Antikörper

IFNGR1/CD119 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1H3A4

Kat-Nr. : 66704-1-PBS

Synonyme

IFNGR1, 1H3A4, CD119, IFN gamma R1, IFN gamma receptor 1

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  WB analysis of HeLa using 66704-1-Ig (same clone as 66704-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 66704-1-Ig (IFNGR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66704-1-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 66704-1-Ig (same clone as 66704-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 66704-1-Ig (IFNGR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66704-1-PBS in a different storage buffer formulation.

• 

  WB analysis of T-47D using 66704-1-Ig (same clone as 66704-1-PBS)

  T-47D cells were subjected to SDS PAGE followed by western blot with 66704-1-Ig (IFNGR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66704-1-PBS in a different storage buffer formulation.

• 

  WB analysis of Jurkat using 66704-1-Ig (same clone as 66704-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 66704-1-Ig (IFNGR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66704-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

66704-1-PBS bindet in WB, Indirect ELISA IFNGR1/CD119 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: IFNGR1/CD119 fusion protein Ag27085
• Vollständiger Name: interferon gamma receptor 1
• Berechnetes Molekulargewicht: 54 kDa
• Beobachtetes Molekulargewicht: 90 kDa
• GenBank-Zugangsnummer: BC005333
• Gene symbol: IFNGR1
• Gene ID (NCBI): 3459
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Interferon-gamma (IFN-γ) is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Cellular responses to IFN-γ are activated through its interaction with a heterodimeric receptor consisting of two subunits, IFNGR1 (CD119) and IFNGR2. IFNGR1 is the ligand-binding subunit which binds IFN-γ with high affinity, whereas IFNGR2 serves as the accessory subunit. Two subunits bind one IFN-γ dimer. Defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. (PMID: 17981204; 946248; 10888113)