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IGFALS Polyklonaler Antikörper

IGFALS Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24545-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of human plasma using IGFALS Polyclonal antibody (24545-1-AP)

    WB analysis of human plasma using 24545-1-AP (same clone as 24545-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 24545-1-AP (IGFALS antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24545-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

24545-1-PBS bindet in WB, Indirect ELISA IGFALS und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen IGFALS fusion protein Ag21696
Vollständiger Name insulin-like growth factor binding protein, acid labile subunit
Berechnetes Molekulargewicht 605 aa, 66 kDa
Beobachtetes Molekulargewicht85 kDa
GenBank-ZugangsnummerBC025681
Gene symbol IGFALS
Gene ID (NCBI) 3483
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

THE ACID-LABILE SUBUNIT (ALS), a liver-derived, GH-dependent, 85-kD glycoprotein, is a key component of the 150-kD IGF circulating ternary complex(PMID: 17726072). The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.