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IGFBP4 Polyklonaler Antikörper

IGFBP4 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30952-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using IGFBP4 Polyclonal antibody (30952-1-AP)

    WB analysis using 30952-1-AP (same clone as 30952-1-PBS)

    MDA-MB-231 cells lysates were subjected to SDS PAGE followed by western blot with 30952-1-AP (IGFBP4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30952-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30952-1-PBS bindet in WB, Indirect ELISA IGFBP4 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name insulin-like growth factor binding protein 4
Berechnetes Molekulargewicht28 kDa
Beobachtetes Molekulargewicht 28-40 kDa
GenBank-ZugangsnummerNM_001552.3
Gene symbol IGFBP4
Gene ID (NCBI) 3487
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IGFBP4, also named as IBP4, is a 258 amino acid protein, which contains one IGFBP N-terminal domain and one thyroglobulin type-1 domain. IGFBP4 is the smallest member of the insulin-like growth factor binding protein family (IGFBP). It is a hepatic protein that plays a role in modulating the activity and bioavailability of IGF-I. The expression of IGFBP4 was found to increase under conditions of hypoxia. IGFBP4 is highly expressed in adipocytes and osteoblasts and is inhibitory of IGFs in vitro. (PMID: 28938423, PMID: 34646401).