IKBKAP Polyklonaler Antikörper

IKBKAP Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31705-1-PBS

Synonyme

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  WB analysis using 31705-1-AP (same clone as 31705-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31705-1-AP (IKBKAP antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31705-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

31705-1-PBS bindet in WB, Indirect ELISA IKBKAP und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: IKBKAP fusion protein Ag35286
• Vollständiger Name: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
• Berechnetes Molekulargewicht: 150kDa，1332aa
• Beobachtetes Molekulargewicht: 140-150 kDa
• GenBank-Zugangsnummer: NM_001318360.1
• Gene symbol: IKBKAP
• Gene ID (NCBI): 8518
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IKBKAP, also known as ELP1. It is expected to be located in the cytoplasm and nucleus, which is ubiquitinated in adrenal and ovary tissue. The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. And it exists in homodimer. The molecular weight of IKBKAP is 150 kDa.