IKZF4 Polyklonaler Antikörper
IKZF4 Polyklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 31094-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
31094-1-PBS bindet in WB, Indirect ELISA IKZF4 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | IKZF4 fusion protein Ag34767 |
| Vollständiger Name | IKAROS family zinc finger 4 (Eos) |
| Beobachtetes Molekulargewicht | 64-70 kDa |
| GenBank-Zugangsnummer | BC160169 |
| Gene symbol | IKZF4 |
| Gene ID (NCBI) | 64375 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
IKZF4 is a member of the Ikaros family transcription factors. The Ikaros family was originally designated to function in hematopoiesis, but it is only recently that studies have begun to show the relevance of this family in T helper cell differentiation. IKZF3 was preferentially expressed in TH17 cells and governs TH17 differentiation by silencing IL-2 expression. By investigating the dynamics of the TH17 regulatory network, IKZF4 was proposed by Yosef et al. as a composite in the negative regulatory module for TH17. (PMID: 24644282)

