IKZF4 Polyklonaler Antikörper

IKZF4 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31094-1-PBS

Synonyme

EOS, IKZF 4, KIAA1782, Zinc finger protein Eos, ZNFN1A4



Geprüfte Anwendungen

Produktinformation

31094-1-PBS bindet in WB, Indirect ELISA IKZF4 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen IKZF4 fusion protein Ag34767
Vollständiger Name IKAROS family zinc finger 4 (Eos)
Beobachtetes Molekulargewicht64-70 kDa
GenBank-ZugangsnummerBC160169
Gene symbol IKZF4
Gene ID (NCBI) 64375
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IKZF4 is a member of the Ikaros family transcription factors. The Ikaros family was originally designated to function in hematopoiesis, but it is only recently that studies have begun to show the relevance of this family in T helper cell differentiation. IKZF3 was preferentially expressed in TH17 cells and governs TH17 differentiation by silencing IL-2 expression. By investigating the dynamics of the TH17 regulatory network, IKZF4 was proposed by Yosef et al. as a composite in the negative regulatory module for TH17. (PMID: 24644282)