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IL-1 beta Polyklonaler Antikörper

IL-1 beta Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30234-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using IL-1 beta Polyclonal antibody (30234-1-AP)

    WB analysis using 30234-1-AP (same clone as 30234-1-PBS)

    Untreated, LPS and Protein transport inhibitor treated THP-1 cells were subjected to SDS PAGE followed by western blot with 30234-1-AP (IL1B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30234-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of U-87 MG cells using IL-1 beta Polyclonal antibody (30234-1-AP)

    WB analysis of U-87 MG using 30234-1-AP (same clone as 30234-1-PBS)

    U-87 MG cells were subjected to SDS PAGE followed by western blot with 30234-1-AP (IL1B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30234-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30234-1-PBS bindet in WB, Indirect ELISA IL-1 beta und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen IL-1 beta fusion protein Ag30574
Vollständiger Name interleukin 1, beta
Berechnetes Molekulargewicht 31 kDa
Beobachtetes Molekulargewicht31 kDa
GenBank-ZugangsnummerNM_000576
Gene symbol IL1B
Gene ID (NCBI) 3553
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Interleukin-1, produced mainly by blood monocytes, mediates the panoply of host reactions collectively known as acute phase response. It is identical to endogenous pyrogen. The multiple biologic activities that define IL1 are properties of a 15- to 18-kD protein that is derived from a 30- to 35-kD precursor. Interleukin 1β (IL-1B) is a member of the interleukin 1 cytokine family. It is a pro-inflammatory cytokine against infection, playing an important role in the pathogenesis of cancers. It signals through various adaptor proteins and kinases that lead to activation of numerous downstream targets