IL-1 beta Rekombinanter Antikörper

IL-1 beta Rekombinant Antikörper für FC (Intra)

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Ratte

Anwendung

FC (Intra)

Konjugation

Unkonjugiert

CloneNo.

241001F11

Kat-Nr. : 98310-2-PBS

Synonyme

Il1 beta, Il1b, IL 1 beta, IL-1 beta,IL 1 beta,IL1beta, IL-1 β

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  FC experiment of Transfected HEK-293T using 98310-2-RR (same clone as 98310-2-PBS)

  1x10^6 HEK-293T cells or IL-1 beta transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Rat Il1 beta Rabbit RecAb (98310-2-RR, Clone: 241001F11) and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98310-2-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected HEK-293T using 98310-2-RR (same clone as 98310-2-PBS)

  1x10^6 HEK-293T cells or IL-1 beta transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Rat Il1 beta Rabbit RecAb (98310-2-RR, Clone: 241001F11) and Multi-rAb CoraLite ® Plus 647-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR005) (red), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98310-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98310-2-PBS bindet in FC (Intra) IL-1 beta und zeigt Reaktivität mit Ratten

• Getestete Reaktivität: Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: interleukin 1 beta
• Berechnetes Molekulargewicht: 31 kDa
• GenBank-Zugangsnummer: NM_031512
• Gene symbol: IL-1 beta
• Gene ID (NCBI): 24494
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

Interleukin-1, produced mainly by blood monocytes, mediates the panoply of host reactions collectively known as acute phase response. It is identical to endogenous pyrogen. The multiple biologic activities that define IL1 are properties of a 15- to 18-kD protein that is derived from a 30- to 35-kD precursor. Interleukin 1β (IL-1B) is a member of the interleukin 1 cytokine family. It is a pro-inflammatory cytokine against infection, playing an important role in the pathogenesis of cancers. It signals through various adaptor proteins and kinases that lead to activation of numerous downstream targets.