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IL-13RA2 Rekombinanter Antikörper

IL-13RA2 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242742F11

Kat-Nr. : 85631-1-PBS

Synonyme

CD213a2, IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, Il13ra2, IL-13R-alpha-2

Filter:
  • Western Blot (WB) analysis of various lysates using IL-13RA2 Recombinant antibody (85631-1-RR)

    WB analysis using 85631-1-RR (same clone as 85631-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85631-1-RR (IL-13RA2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85631-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85631-1-PBS bindet in WB, Indirect ELISA IL-13RA2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen IL-13RA2 fusion protein Eg3118
Vollständiger Name interleukin 13 receptor, alpha 2
Berechnetes Molekulargewicht44 kDa
Beobachtetes Molekulargewicht65 kDa
GenBank-ZugangsnummerNM_008356.4
Gene symbol Il13ra2
Gene ID (NCBI) 16165
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IL13RA2, also named as IL13R and CD213a2, belongs to the type I cytokine receptor family. It binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). IL13RA2 lacks the cytoplasmic domain for signaling, indicating that it acts as a decoy receptor. IL13RA2 gene polymorphisms have been associated with systemic sclerosis (PMID: 16981293). Overexpression of IL13RA2 gene has been reported in several types of cancer, including melanoma, lung cancer, and brain tumor, which makes it a potential immunotherapeutic target (PMID: 19895199; 24970476; 24021875).