IL-13RA2 Rekombinanter Antikörper

IL-13RA2 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242742C4

Kat-Nr. : 98407-3-RR

Synonyme

CD213a2, IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, Il13ra2, IL-13R-alpha-2

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  FC experiment of Transfected HEK-293T using 98407-3-RR

  1x10^6 HEK-293T cells (left) and IL-13RA2-transfected HEK-293T cells (right) were surface stained with 0.25 ug Anti-Mouse IL-13RA2 Rabbit RecAb (98407-3-RR, Clone: 242742C4) and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  FC experiment of Transfected HEK-293T using 98407-3-RR

  1x10^6 HEK-293T cells (left) and IL-13RA2-transfected HEK-293T cells (right) were surface stained with 0.25 ug Anti-Mouse IL-13RA2 Rabbit RecAb (98407-3-RR, Clone: 242742C4) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-2-RR, Clone: 240953A11) (blue), and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Transfected HEK-293T cells

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98407-3-RR bindet in FC IL-13RA2 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: IL-13RA2 fusion protein Eg3118
• Vollständiger Name: interleukin 13 receptor, alpha 2
• Berechnetes Molekulargewicht: 44 kDa
• GenBank-Zugangsnummer: NM_008356.4
• Gene symbol: Il13ra2
• Gene ID (NCBI): 16165
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

IL-13RA2, also named as IL-13R and CD213a2, belongs to the type I cytokine receptor family. It binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). IL-13RA2 lacks the cytoplasmic domain for signaling, indicating that it acts as a decoy receptor. IL-13RA2 gene polymorphisms have been associated with systemic sclerosis (PMID: 16981293). Overexpression of IL-13RA2 gene has been reported in several types of cancer, including melanoma, lung cancer, and brain tumor, which makes it a potential immunotherapeutic target (PMID: 19895199; 24970476; 24021875).