IL-13Ra1/CD213a1 Rekombinanter Antikörper

IL-13Ra1/CD213a1 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Biotin

CloneNo.

241834A1

Kat-Nr. : Biotin-FcA98216

Synonyme

IL13RA1, Cancer/testis antigen 19, CD213A1, CT19, IL 13 receptor subunit alpha 1

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  FC experiment of MCF-7 using Biotin-FcA98216

  1x10^6 MCF-7 cells (left) or Jurkat cells (right) were surface stained with 0.25 ug Biotin Anti-Human IL-13Ra1/CD213a1 Rabbit RecAb (Biotin-FcA98216, Clone: 241834A1) (red) or FcZero-rAb™ Biotin Rabbit IgG Isotype Control Recombinant Antibody (Biotin-FcA98136, Clone: 240953C9) (blue), and Streptavidin-PE Conjugate (Cat.No. PE-PF00030). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: MCF-7-Zellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

Biotin-FcA98216 bindet in FC IL-13Ra1/CD213a1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: IL-13Ra1/CD213a1 fusion protein Eg2320
• Vollständiger Name: interleukin 13 receptor, alpha 1
• Berechnetes Molekulargewicht: 49 kDa
• GenBank-Zugangsnummer: BC009960
• Gene symbol: IL-13Rα1
• Gene ID (NCBI): 3597
• Konjugation: Biotin
• Excitation/Emission maxima wavelengths: -
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

IL-13 is an immunoregulatory cytokine secreted predominantly by activated T-helper 2 (Th2) cells and performs multiple functions through a complex receptor system comprised of IL-4Rα and two IL-13 binding proteins, IL-13Rα1 and IL-13Rα2 (PMID: 12704343). IL-13Rα1 is a glycosylated transmembrane protein (PMID: 10856136; 9723655). IL-13Rα1 is expressed on a wide range of cells including B cells, monocytes, macrophages, basophils, mast cells, and endothelial cells (PMID: 10856136; 31866859). IL-13 binding to the IL-4Rα/IL-13Rα1 complex leads to activation of JAK1, JAK2, and TYK2 and subsequent phosphorylation of STAT6 and STAT3 (PMID: 31866859).