IL-17RA Rekombinanter Antikörper

IL-17RA Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

250349C6

Kat-Nr. : 98532-2-PBS

Synonyme

CD217, IL-17 receptor A, Il17r, Il17ra, Interleukin-17 receptor A

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  FC experiment of mouse bone marrow cells using 98532-2-RR (same clone as 98532-2-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse IL-17RA Rabbit RecAb (98532-2-RR, Clone: 250349C6) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse Ly-6G/Ly-6C (Gr-1). Cells were not fixed. This data was developed using the same antibody clone with 98532-2-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse bone marrow cells using 98532-2-RR (same clone as 98532-2-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse IL-17RA Rabbit RecAb (98532-2-RR, Clone: 250349C6) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98532-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98532-2-PBS bindet in FC IL-17RA und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: IL-17RA fusion protein Eg2584
• Vollständiger Name: interleukin 17 receptor A
• Berechnetes Molekulargewicht: 98kDa
• GenBank-Zugangsnummer: NM_008359.2
• Gene symbol: Il17ra
• Gene ID (NCBI): 16172
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

IL-17 is a proinflammatory cytokine. IL-17 can signal as homodimers or heterodimers through a heterodimeric receptor formed by IL-17 receptor A (IL-17RA) and IL-17 receptor C (IL-17RC) subunits. IL-17RA is ubiquitously expressed in both the epithelial and hematopoietic cell compartments. IL-17/IL-17RA signaling plays an important physiological role in regulating the mucosal host defense against invading microorganisms, but it can also play pathogenic roles in several inflammatory or autoimmune conditions; furthermore, it has been described as pro-tumorigenic in several cancer types.