IL-17RA Rekombinanter Antikörper

IL-17RA Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

250349C6

Kat-Nr. : 98532-2-RR

Synonyme

CD217, IL-17 receptor A, Il17r, Il17ra, Interleukin-17 receptor A

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  FC experiment of mouse bone marrow cells using 98532-2-RR

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse IL-17RA Rabbit RecAb (98532-2-RR, Clone: 250349C6) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse Ly-6G/Ly-6C (Gr-1). Cells were not fixed.

• 

  FC experiment of mouse bone marrow cells using 98532-2-RR

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse IL-17RA Rabbit RecAb (98532-2-RR, Clone: 250349C6) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Knochenmarkzellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98532-2-RR bindet in FC IL-17RA und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: IL-17RA fusion protein Eg2584
• Vollständiger Name: interleukin 17 receptor A
• Berechnetes Molekulargewicht: 98kDa
• GenBank-Zugangsnummer: NM_008359.2
• Gene symbol: Il17ra
• Gene ID (NCBI): 16172
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

IL-17 is a proinflammatory cytokine. IL-17 can signal as homodimers or heterodimers through a heterodimeric receptor formed by IL-17 receptor A (IL-17RA) and IL-17 receptor C (IL-17RC) subunits. IL-17RA is ubiquitously expressed in both the epithelial and hematopoietic cell compartments. IL-17/IL-17RA signaling plays an important physiological role in regulating the mucosal host defense against invading microorganisms, but it can also play pathogenic roles in several inflammatory or autoimmune conditions; furthermore, it has been described as pro-tumorigenic in several cancer types.