IL-1R2 Monoklonaler Antikörper

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• KD/KO Validated

IL-1R2 Monoklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human, Maus

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3H4H4

Kat-Nr. : 60262-1-PBS

Synonyme

IL1R2, 3H4H4, CD121 antigen-like family member B, CD121b, IL 1R 2

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  WB analysis of HeLa using 60262-1-Ig (same clone as 60262-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 60262-1-Ig (IL1R2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60262-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 60262-1-Ig (same clone as 60262-1-PBS)

  Immunofluorescent analysis of HeLa cells using 60262-1-Ig (IL1R2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Mouse IgG (H+L). This data was developed using the same antibody clone with 60262-1-PBS in a different storage buffer formulation.

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  IF Staining of Jurkat using 60262-1-Ig (same clone as 60262-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed Jurkat cells using IL-1R2 antibody (60262-1-Ig, Clone: 3H4H4 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1). This data was developed using the same antibody clone with 60262-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

60262-1-PBS bindet in WB, IF/ICC, Indirect ELISA IL-1R2 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: IL-1R2 fusion protein Ag4495
• Vollständiger Name: interleukin 1 receptor, type II
• Berechnetes Molekulargewicht: 398 aa, 45 kDa
• Beobachtetes Molekulargewicht: 45 kDa
• GenBank-Zugangsnummer: BC039031
• Gene symbol: IL1R2
• Gene ID (NCBI): 7850
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Interleukin-1 receptor type 2 (IL1R2, also known as CD121b) is a cytokine receptor that belongs to the interleukin 1 receptor family. It exists in both a membrane bound and soluble form. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 serves as a negative regulator of IL-1 signaling, thereby suppressing inflammatory response.