IL-1R2 Rekombinanter Antikörper

IL-1R2 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242602C1

Kat-Nr. : 98347-1-PBS

Synonyme

IL-1R-2, Il1r2, IL-1 type II receptor, CD121b, CD121 antigen-like family member B

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  FC experiment of mouse bone marrow cells using 98347-1-RR (same clone as 98347-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse IL-1R2 Rabbit RecAb (98347-1-RR, Clone: 242602C1) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-conjugated Goat Anti-Rabbit IgG. Cells were not fixed. This data was developed using the same antibody clone with 98347-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse bone marrow cells using 98347-1-RR (same clone as 98347-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse IL-1R2 Rabbit RecAb (98347-1-RR, Clone:242602C1) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were not fixed. This data was developed using the same antibody clone with 98347-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98347-1-PBS bindet in FC IL-1R2 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: interleukin 1 receptor, type II
• Berechnetes Molekulargewicht: 46 kDa
• GenBank-Zugangsnummer: NM_010555.4
• Gene symbol: Il1r2
• Gene ID (NCBI): 16178
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

Interleukin-1 receptor type 2 (IL1R2, also known as CD121b) is a cytokine receptor that belongs to the interleukin 1 receptor family. It exists in both a membrane bound and soluble form. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 serves as a negative regulator of IL-1 signaling, thereby suppressing inflammatory response.