IL-1RAP Rekombinanter Antikörper

IL-1RAP Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

FITC Plus Fluorescent Dye

CloneNo.

240756A12

Kat-Nr. : FITC-98073

Synonyme

IL1RAP, 240756A12, C3orf13, EC:3.2.2.6, IL 1R 3

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  FC experiment of human PBMCs using FITC-98073

  1x10^6 FC receptor blocked human PBMCs were surface stained with APC Anti-Human CD14, and 5 ul FITC Plus Anti-Human IL-1RAP Rabbit RecAb (FITC-98073, Clone: 240756A12) or FITC Plus Rabbit IgG Isotype Control RecAb (FITC-98136, Clone: 240953C9). Cells were not fixed.

• 

  FC experiment of human PBMCs using FITC-98073

  1x10^6 FC receptor blocked human PBMCs were surface stained with 5 ul FITC Plus Anti-Human IL-1RAP Rabbit RecAb (FITC-98073, Clone: 240756A12) (red) or FITC Plus Rabbit IgG Isotype Control RecAb (FITC-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: humane PBMCs

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Produktinformation

FITC-98073 bindet in FC IL-1RAP und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: IL-1RAP fusion protein Eg0827
• Vollständiger Name: interleukin 1 receptor accessory protein
• Berechnetes Molekulargewicht: 65 kDa
• GenBank-Zugangsnummer: NM_002182.4
• Gene symbol: IL1RAP
• Gene ID (NCBI): 3556
• Konjugation: FITC Plus Fluorescent Dye
• Excitation/Emission maxima wavelengths: 495 nm / 524 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

IL-1RAP (Interleukin-1 receptor accessory protein), also known as IL-1RAcP, IL-1R-3, or IL-1R3, is a member of the interleukin-1 receptor family. IL-1RAP is composed of an extracellular region containing three Ig-like C2 type domains, a transmembrane region, and a cytoplasmic region with a TIR (Toll-IL-1-receptor) domain. IL-1RAP functions as a co-receptor for IL-1, IL-33, IL-36. It plays an essential role in the signaling of the IL-1 family cytokines such as IL-1, IL-33, and IL-36, as well as tyrosine kinases FLT3 and c-Kit. IL-1RAP can also exist in a soluble form.