IL-21R Polyklonaler Antikörper

IL-21R Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10533-1-PBS

Synonyme

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  WB analysis using 10533-1-AP (same clone as 10533-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 10533-1-AP (IL21R antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10533-1-PBS in a different storage buffer formulation.

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  WB analysis of K-562 using 10533-1-AP (same clone as 10533-1-PBS)

  K-562 cells were subjected to SDS PAGE followed by western blot with 10533-1-AP (IL21R antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10533-1-PBS in a different storage buffer formulation.

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  WB analysis of COLO 320 using 10533-1-AP (same clone as 10533-1-PBS)

  COLO 320 cells were subjected to SDS PAGE followed by western blot with 10533-1-AP (IL21R antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10533-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse thymus using 10533-1-AP (same clone as 10533-1-PBS)

  mouse thymus tissue were subjected to SDS PAGE followed by western blot with 10533-1-AP (IL21R antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10533-1-PBS in a different storage buffer formulation.

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  WB analysis of Raji using 10533-1-AP (same clone as 10533-1-PBS)

  Raji cells were subjected to SDS PAGE followed by western blot with 10533-1-AP (IL21R antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10533-1-PBS in a different storage buffer formulation.

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  IHC staining of human lymphoma using 10533-1-AP (same clone as 10533-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 10533-1-AP (IL21R Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 10533-1-PBS in a different storage buffer formulation.

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  IHC staining of human lymphoma using 10533-1-AP (same clone as 10533-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 10533-1-AP (IL21R Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 10533-1-PBS in a different storage buffer formulation.

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  IF Staining of COLO 320 using 10533-1-AP (same clone as 10533-1-PBS)

  Immunofluorescent analysis of COLO 320 cells using 10533-1-AP (IL21R antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 10533-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

10533-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA IL-21R und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: IL-21R fusion protein Ag0762
• Vollständiger Name: interleukin 21 receptor
• Berechnetes Molekulargewicht: 59 kDa
• Beobachtetes Molekulargewicht: 68-70 kDa
• GenBank-Zugangsnummer: BC004348
• Gene symbol: IL-21R
• Gene ID (NCBI): 50615
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IL21R, a receptor for interleukin-21, belongs to the type I cytokine receptor family. IL21R has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3.

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