IL-21R Monoklonaler Antikörper

IL-21R Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1D1C2

Kat-Nr. : 66319-1-PBS

Synonyme

IL21R, IL-21 receptor, IL 21R, IL 21 receptor, CD360

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  WB analysis using 66319-1-Ig (same clone as 66319-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66319-1-Ig (IL-21R antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66319-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 66319-1-Ig (same clone as 66319-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66319-1-Ig (IL-21R antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66319-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 66319-1-Ig (same clone as 66319-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66319-1-Ig (IL-21R antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66319-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 66319-1-Ig (same clone as 66319-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66319-1-Ig (IL21R antibody) at dilution of 1:100 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66319-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 66319-1-Ig (same clone as 66319-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 66319-1-Ig (IL21R antibody) at dilution of 1:100 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66319-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

66319-1-PBS bindet in WB, IHC, Indirect ELISA IL-21R und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2b
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: IL-21R fusion protein Ag21295
• Vollständiger Name: interleukin 21 receptor
• Berechnetes Molekulargewicht: 59 kDa
• Beobachtetes Molekulargewicht: 55-65 kDa
• GenBank-Zugangsnummer: BC004348
• Gene symbol: IL-21R
• Gene ID (NCBI): 50615
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IL21R, a receptor for interleukin-21, belongs to the type I cytokine receptor family. IL21R has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3.