IL-23R Polyklonaler Antikörper

IL-23R Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27163-1-PBS

Synonyme

IL23R, Interleukin-23 receptor, interleukin 23 receptor, IL-23 receptor, IL 23R

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  WB analysis using 27163-1-AP (same clone as 27163-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27163-1-AP (IL23R antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27163-1-PBS in a different storage buffer formulation.

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  WB analysis using 27163-1-AP (same clone as 27163-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27163-1-AP (IL23R antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27163-1-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 27163-1-AP (same clone as 27163-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 27163-1-AP (IL23R antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27163-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 27163-1-AP (same clone as 27163-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 27163-1-AP (IL23R antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27163-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

27163-1-PBS bindet in WB, IHC, Indirect ELISA IL-23R und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: IL-23R fusion protein Ag25939
• Vollständiger Name: interleukin 23 receptor
• Berechnetes Molekulargewicht: 72 kDa
• Beobachtetes Molekulargewicht: 65-75 kDa
• GenBank-Zugangsnummer: NM_144701
• Gene symbol: IL-23R
• Gene ID (NCBI): 149233
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Interleukin-23 receptor (IL-23R) is a type I cytokine receptor that plays a critical role in immune responses and inflammation. It forms a receptor complex with IL-12Rβ1 and is activated by the cytokine IL-23, which is primarily produced by dendritic cells and activated macrophages (PMID: 39796684). The genetic and epigenetic interactions in the IL-23R/IL-17 axis are associated with elevated expression of IL-17 and inflammatory bowel disease (IBD) pathogenesis (PMID: 21672939).