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IL-27A p28 Monoklonaler Antikörper

IL-27A p28 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1E1H5

Kat-Nr. : 66164-1-PBS

Synonyme

IL27, IL-27, IL 27, IL 27 A, IL 27 subunit alpha

Filter:
  • Western Blot (WB) analysis of Recombinant protein using IL-27A p28 Monoclonal antibody (66164-1-Ig)

    WB analysis of Recombinant protein using 66164-1-Ig (same clone as 66164-1-PBS)

    IL27 fusion protein were subjected to SDS PAGE followed by western blot with 66164-1-Ig (IL-27 antibody at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66164-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

66164-1-PBS bindet in WB, Indirect ELISA IL-27A p28 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen IL-27A p28 fusion protein Ag21436
Vollständiger Name interleukin 27
Berechnetes Molekulargewicht 243 aa, 27 kDa
Beobachtetes Molekulargewicht 31 kDa
GenBank-ZugangsnummerBC062422
Gene symbol IL-27
Gene ID (NCBI) 246778
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IL-27, as a member of the IL-6/IL-12 family, is a heterodimeric cytokine composed of two subunits: p28 (IL-27a) and EBI3 (IL-27b). IL-27 acts on various cell types, including T cells, B cells, macrophages, dendritic cells, natural killer (NK) cells and non-hematopoietic cells. IL-27 plays a critical role in the early regulation of T helper type 1 initiation, and enhances proliferation of naive CD4+T cells and naive B cells. It, however, also exerts anti-inflammatory functions by inhibiting the development of Th17 cells and inducing IL-10 producing type 1 regulatory T cells. IL-27 is a potentially promising cytokine for therapeutic approaches on various human diseases.