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IL-27RA Polyklonaler Antikörper

IL-27RA Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12308-1-PBS

Synonyme

IL27RA, IL 27R alpha, IL 27 receptor subunit alpha, Cytokine receptor-like 1, Cytokine receptor WSX-1

Filter:
  • Western Blot (WB) analysis of various lysates using IL-27RA Polyclonal antibody (12308-1-AP)

    WB analysis using 12308-1-AP (same clone as 12308-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 12308-1-AP (IL-27RA antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12308-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

12308-1-PBS bindet in WB, Indirect ELISA IL-27RA und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen IL-27RA fusion protein Ag2956
Vollständiger Name interleukin 27 receptor, alpha
Berechnetes Molekulargewicht 636 aa, 69 kDa
Beobachtetes Molekulargewicht70 kDa
GenBank-ZugangsnummerBC028003
Gene symbol IL27RA
Gene ID (NCBI) 9466
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IL-27RA, also known as T-cell cytokine receptor WSX-1 or TCCR, is a unique receptor subunit for the cytokine IL-27. It is expressed in a variety of cells including activated T cells, NK cells, mast cells, endothelial cells, activated B cells, monocytes, Langerhans cells, and activated dendritic cells (PMID: 18378322). The interaction with IL-27 leads to the phosphorylation of Jak and STAT proteins, which are crucial for the regulation of immune responses (PMID: 28536468). IL-27RA plays a significant role in immune cell activation and differentiation, particularly in the context of Th1 and Th17 cells (PMID: 38566992).