IL-28B Rekombinanter Antikörper

IL-28B Rekombinant Antikörper für FC (Intra)

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC (Intra)

Konjugation

Unkonjugiert

CloneNo.

250563C9

Kat-Nr. : 98567-3-PBS

Synonyme

Ifnl3, IFN-lambda-3, Il28, Il28b, Interferon lambda-3

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  FC experiment of Transfected HEK-293T using 98567-3-RR (same clone as 98567-3-PBS)

  1x10^6 HEK-293T cells (left) or IL-28B transfected HEK-293T cells (right) were stained with 0.25 ug Anti-Mouse IL-28B Rabbit RecAb (98567-3-RR, Clone: 250563C9) and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98567-3-PBS in a different storage buffer formulation.

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  FC experiment of Transfected HEK-293T using 98567-3-RR (same clone as 98567-3-PBS)

  1x10^6 HEK-293T cells (left) or IL-28B transfected HEK-293T cells (right) were stained with 0.25 ug Anti-Mouse IL-28B Rabbit RecAb (98567-3-RR, Clone: 250563C9) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9)(blue), and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98567-3-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98567-3-PBS bindet in FC (Intra) IL-28B und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: IL-28B fusion protein Eg3146
• Vollständiger Name: interleukin 28B
• Berechnetes Molekulargewicht: 22 kDa
• GenBank-Zugangsnummer: NM_177396.1
• Gene symbol: Il28b
• Gene ID (NCBI): 338374
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

IL-28B is a type III IFN, which shares many of the biological effects of type I IFNs but may have fewer side effects due to a more selective receptor distribution. It interacts with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA) (PMID: 20712453;12469119;16539846).