IL-29 Rekombinanter Antikörper

IL-29 Rekombinant Antikörper für FC (Intra)

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC (Intra)

Konjugation

Unkonjugiert

CloneNo.

250226G7

Kat-Nr. : 98504-1-PBS

Synonyme

IL29, Cytokine Zcyto21, IFN lambda 1, IFNL1, IFN-lambda-1

---

• 

  FC experiment of Transfected CHO using 98504-1-RR (same clone as 98504-1-PBS)

  1x10^6 CHO cells or IL-29 transfected CHO cells were intracellularly stained with0.25 ug Anti-Human IL-29 Rabbit RecAb (98504-1-RR, Clone: 250226G7) and PE-conjugated Goat Anti-Rabbit IgG. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98504-1-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected CHO using 98504-1-RR (same clone as 98504-1-PBS)

  1x10^6 CHO cells or IL-29 transfected CHO cells were intracellularly stained with 0.25 ug Anti-Human IL-29 Rabbit RecAb (98504-1-RR, Clone: 250226G7) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98504-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

98504-1-PBS bindet in FC (Intra) IL-29 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: IL-29 fusion protein Eg2843
• Vollständiger Name: interleukin 29 (interferon, lambda 1)
• Berechnetes Molekulargewicht: 22 kDa
• GenBank-Zugangsnummer: NM_172140.1
• Gene symbol: IL-29
• Gene ID (NCBI): 282618
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

Interleukin-29 (IL-29) is a cytokine belonging to the Type III interferon family, which has another two subfamilies IL-28A and IL-28B. They are also known as IFN-λ1, IFN-λ2 and IFN-λ3, respectively. IL-29 is produced predominantly by maturing dendritic cells and macrophages. IL-29 plays an important role in the immune response against pathogenes and especially against viruses by mechanisms similar to type I interferons. IL-29 receptor signals through JAK-STAT pathways leading to activated expression of interferon-stimulated genes and production of antiviral proteins.