IL-2RG Polyklonaler Antikörper

IL-2RG Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11409-1-PBS

Synonyme



Geprüfte Anwendungen

Produktinformation

11409-1-PBS bindet in WB, Indirect ELISA IL-2RG und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen IL-2RG fusion protein Ag1911
Vollständiger Name interleukin 2 receptor, gamma (severe combined immunodeficiency)
Berechnetes Molekulargewicht 369 aa, 42 kDa
Beobachtetes Molekulargewicht 64-70 kDa
GenBank-ZugangsnummerBC014972
Gene symbol IL2RG
Gene ID (NCBI) 3561
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The interleukin-2 receptor (IL-2R) is a heterotrimeric receptor consisting of three subunits, alpha (IL-2RA), beta (IL-2RB), and gamma (IL-2RG). IL-2RG, also known as CD132, is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in the gene of IL-2RG cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.