IL-3RB/CD131 Rekombinanter Antikörper

IL-3RB/CD131 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

241823B12

Kat-Nr. : 98336-2-RR

Synonyme

CSF2RB, CD131, CDw131, GM-CSF/IL-3/IL-5 receptor common beta subunit, IL3RB

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  FC experiment of Transfected HEK-293T using 98336-2-RR

  1x10^6 HEK-293T cells (left) or IL-3RB/CD131-transfected HEK-293T cells (right) were surface stained with 0.25 ug Anti-Human IL-3 R Beta/CD131 Rabbit RecAb (98336-2-RR, Clone:241823B12) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  FC experiment of Transfected HEK-293T using 98336-2-RR

  1x10^6 HEK-293T cells(left) or IL-3RB/CD131-transfected HEK-293T cells(right) were surface stained with 0.25 ug Anti-Human IL-3 R Beta/CD131 Rabbit RecAb (98336-2-RR, Clone:241823B12)(red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Transfected HEK-293T cells

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98336-2-RR bindet in FC IL-3RB/CD131 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: IL-3RB/CD131 fusion protein Eg1662
• Vollständiger Name: colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
• Berechnetes Molekulargewicht: 97kDa
• GenBank-Zugangsnummer: NM_000395.3
• Gene symbol: CSF2RB
• Gene ID (NCBI): 1439
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

IL-3RB/CD131, also known as CSF2RB, is the common subunit of the type I cytokine receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3 and IL-5. CD131 is expressed on various immune cells, including hematopoietic progenitor cells, granulocytes, monocytes, macrophages, eosinophils, and mast cells, which plays a crucial role in mediating the effects of cytokines (PMID: 18412971). Tregs of healthy donors constitutively transcribe CSF2RB, but protein expression was much higher after TCR stimulation (PMID: 36532080, 3557440).