IL-4 Rekombinanter Antikörper

IL-4 Rekombinant Antikörper für FC (Intra)

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Ratte

Anwendung

FC (Intra)

Konjugation

Unkonjugiert

CloneNo.

241249H7

Kat-Nr. : 98255-1-PBS

Synonyme

241249H7, B-cell growth factor 1, B-cell IGG differentiation factor, B-cell stimulatory factor 1, BSF-1

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  FC experiment of Transfected HEK-293T using 98255-1-RR (same clone as 98255-1-PBS)

  1x10^6 HEK-293T cells or IL-4 transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Rat IL-4 Rabbit Recombinant Antibody (98255-1-RR, Clone:241249H7) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98255-1-PBS in a different storage buffer formulation.

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  FC experiment of Transfected HEK-293T using 98255-1-RR (same clone as 98255-1-PBS)

  1x10^6 HEK-293T cells (left) or IL-4 transfected HEK-293T cells (right) were intracellularly stained with 0.25 ug Anti-Rat IL-4 Rabbit Recombinant Antibody (98255-1-RR, Clone:241249H7) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (red), or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98255-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98255-1-PBS bindet in FC (Intra) IL-4 und zeigt Reaktivität mit Ratten

• Getestete Reaktivität: Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: IL-4 fusion protein Eg1113
• Vollständiger Name: interleukin 4
• Berechnetes Molekulargewicht: 16kDa
• GenBank-Zugangsnummer: NM_201270.1
• Gene symbol: IL-4
• Gene ID (NCBI): 287287
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

IL-4 is a cytokine produced by CD4+ T cells in response to helminthes and other extracellular parasites. It promotes the proliferation and differentiation of antigen presenting cells. IL-4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL-4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival.