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IL-4I1 Polyklonaler Antikörper

IL-4I1 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 23048-1-PBS

Synonyme

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  • Western Blot (WB) analysis of various lysates using IL-4I1 Polyclonal antibody (23048-1-AP)

    WB analysis using 23048-1-AP (same clone as 23048-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 23048-1-AP (IL-4I1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23048-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using IL-4I1 Polyclonal antibody (23048-1-AP)

    IF Staining of HeLa using 23048-1-AP (same clone as 23048-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using IL-4I1 antibody (23048-1-AP) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 23048-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

23048-1-PBS bindet in WB, IF/ICC, Indirect ELISA IL-4I1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen IL-4I1 fusion protein Ag19136
Vollständiger Name interleukin 4 induced 1
Berechnetes Molekulargewicht 567 aa, 63 kDa
Beobachtetes Molekulargewicht 70 kDa
GenBank-ZugangsnummerBC131625
Gene symbol IL-4I1
Gene ID (NCBI) 259307
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Interleukin-4 Induced Gene 1 (IL4I1) is a secreted L-phenylalanine oxidase mainly produced by inflammatory antigen-presenting cells-in particular, macrophages present in T helper type 1 granulomas and in various types of tumors. In the last decade, it has been shown that IL4I1 is involved in the fine control of B- and T-cell adaptive immune responses. Preclinical models have revealed its role in cancer immune evasion. Recent clinical data highlight IL4I1 as a new potential prognostic marker in human melanoma. As a secreted enzyme, IL4I1 may represent an easily targetable molecule for cancer immunotherapy. IL4I1 protein has an estimated molecular weight of 75 kDa. (PMID: 31330829, PMID: 21469114)