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IL-5RA/CD125 Rekombinanter Antikörper

IL-5RA/CD125 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242234H8

Kat-Nr. : 84948-5-PBS

Synonyme

IL5RA, IL 5R subunit alpha, IL 5R alpha, IL 5 receptor subunit alpha, HSIL5R3

Filter:
  • Western Blot (WB) analysis of human peripheral blood platelets using IL-5RA/CD125 Recombinant antibody (84948-5-RR)

    WB analysis of human peripheral blood platelets using 84948-5-RR (same clone as 84948-5-PBS)

    human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 84948-5-RR (IL-5 R alpha/CD125 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84948-5-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84948-5-PBS bindet in WB, Indirect ELISA IL-5RA/CD125 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name interleukin 5 receptor, alpha
Berechnetes Molekulargewicht48 kDa
Beobachtetes Molekulargewicht60 kDa
GenBank-ZugangsnummerNM_175726.4
Gene symbol IL-5RA/CD125
Gene ID (NCBI) 3568
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Interleukin-5 receptor subunit alpha (IL-5RA), also known as CD125, is a type I transmembrane protein that belongs to the type I cytokine receptor family. IL-5RA is a critical component of the high-affinity IL-5 receptor complex, IL-5R, which consists of the alpha chain (IL-5RA) that specifically binds to IL-5 and the common beta chain (CD131) shared with receptors for IL-3 and GM-CSF (PMID: 1833065; 7872157). IL-5/IL-5RA signaling axis is crucial for the differentiation, proliferation, recruitment, and activation of eosinophils, and is also involved in pathological eosinophilia (PMID: 34638583).