IL-7 Monoklonaler Antikörper
IL-7 Monoklonal Antikörper für Cytometric bead array, Indirect ELISA
Wirt / Isotyp
Maus / IgG2b
Getestete Reaktivität
human
Anwendung
Cytometric bead array, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
5D5G7
Kat-Nr. : 60206-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
60206-1-PBS bindet in Cytometric bead array, Indirect ELISA IL-7 und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Maus / IgG2b |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | IL-7 fusion protein Ag16314 |
Vollständiger Name | interleukin 7 |
Berechnetes Molekulargewicht | 20 kDa |
GenBank-Zugangsnummer | BC047698 |
Gene symbol | IL-7 |
Gene ID (NCBI) | 3574 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
IL-7 is one of the members of IL-2 superfamily. IL-7 is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells, but is not produced by normal lymphocytes. IL7 plays an active role in the development, survival, maintaining and restoring homeostasis of mature T lymphocytes. It is also a key regulator of the commitment, survival, proliferation and maturation of B cells during development. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can be a potent inducer of proinflammatory cytokines and chemokines which may defend against the infection, but may also mediate destructive lung injury. Elevated serum IL7 levels, together with several other circulating cytokines and chemokines, has been found to be associated with the severity of Coronavirus Disease 19 (COVID-19).