IL-17RA Rekombinanter Antikörper

IL-17RA Rekombinant Antikörper für WB, Sandwich ELISA, Indirect ELISA, Sample test

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Sandwich ELISA, Indirect ELISA, Sample test

Konjugation

Unkonjugiert

CloneNo.

241891E11

Kat-Nr. : 84535-2-PBS

Synonyme

CD217, IL17RA, 241891E11, CANDF5, CDw217

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  WB analysis using 84535-2-RR (same clone as 84535-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84535-2-RR (IL17RA antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84535-2-PBS in a different storage buffer formulation.

• 

  Sandwich ELISA standard curve of MP01397-3

  Sandwich ELISA standard curve of MP01397-3, Human IL17RA Recombinant Matched Antibody Pair - PBS only. 84535-3-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard Eg2317. 84535-2-PBS was HRP conjugated as the detection antibody. Range: 0.156-10 ng/mL

• 

  Sample test of MP01397-3

  The mean IL17RA concentration was determined to be 8.86 ng/mL in MCF-7 cell extract based on a 1.2 mg/mL extract load.

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  Affinity and Kinetic Characterization of 84535-2-RR

  Biolayer interferometry (BLl) kinetic assays of 84535-2-RR against Human IL17RA were performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

Produktinformation

84535-2-PBS bindet in WB, Sandwich ELISA, Indirect ELISA, Sample test IL-17RA und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: IL-17RA fusion protein Eg2317
• Vollständiger Name: interleukin 17 receptor A
• Berechnetes Molekulargewicht: 866 aa, 96 kDa
• Beobachtetes Molekulargewicht: 100-130 kDa
• GenBank-Zugangsnummer: BC011624
• Gene symbol: IL17RA
• Gene ID (NCBI): 23765
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Interleukin-17 receptor A (IL17A) is a major effector cytokine of the innate and adaptive immune system and is involved in antimicrobial host defense and maintenance of tissue integrity. It has been shown that IL-17A is involved in the pathogenesis of asthma and allergy and regulates local immune and inflammatory processes in bone tissue and is involved in the onset and progression of osteoporosis. In addition to this, due to polymorphisms in the IL17RA gene, it leads to the development of Fanconi anemia.