IL-36RN Polyklonaler Antikörper

IL-36RN Polyklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, ELISA

Konjugation

Unkonjugiert

Publikationen(2)

Kat-Nr. : 13113-1-AP

Synonyme

FIL1, FIL1 delta, FIL1(DELTA), FIL1D, IL 1 delta, IL 1 related protein 3, IL 1F5, IL 1HY1, IL 1L1, IL 1ra homolog 1, IL 1RP3, IL1F5, IL-1F5, IL1HY1, IL1L1, IL1RP3, IL-36Ra, IL-36RN, Interleukin 1 delta, Interleukin 1 family member 5, Interleukin 1 HY1, Interleukin 1 like protein 1

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  IHC staining of human skin cancer using 13113-1-AP

  Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 13113-1-AP (IL36RN antibody) at dilution of 1:200 (under 10x lens).

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  IHC staining of human skin cancer using 13113-1-AP

  Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 13113-1-AP (IL36RN antibody) at dilution of 1:200 (under 40x lens).

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  IHC staining of human skin cancer using 13113-1-AP

  Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 13113-1-AP (IL36RN antibody) at dilution of 1:200 (under 10x lens).

• 

  IHC staining of human skin cancer using 13113-1-AP

  Immunohistochemical analysis of paraffin-embedded human skin cancer tissue slide using 13113-1-AP (IL36RN antibody) at dilution of 1:200 (under 40x lens).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IHC: humanes Hautkrebsgewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

• Immunhistochemie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• IHC: See 1 publications below

Produktinformation

13113-1-AP bindet in IHC, ELISA IL-36RN und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: IL-36RN fusion protein Ag3780
• Vollständiger Name: interleukin 1 family, member 5 (delta)
• Berechnetes Molekulargewicht: 155 aa, 17 kDa
• GenBank-Zugangsnummer: BC024747
• Gene symbol: IL-36RN
• Gene ID (NCBI): 26525
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IL36RN is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). It inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling.

Publikationen

Species	Application	Title
human	IHC	PLoS One; Gene signatures associated with barrier dysfunction and infection in oral lichen planus identified by analysis of transcriptomic data; Authors - Phuc Thi-Duy Vo
		Exp Dermatol; Clinical Responses and Transcriptomic Analysis of Spesolimab in a Girl With Severe Dermatitis, Multiple Allergies and Metabolic Wasting Syndrome; Authors - Jinxiang Yang