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IL-4 Rekombinanter Antikörper

IL-4 Rekombinant Antikörper für IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

240794A8

Kat-Nr. : 83894-1-PBS

Synonyme

IL4, 240794A8, B-cell stimulatory factor 1, BSF-1, IL 4

Filter:
  • Immunofluorescence (IF) / fluorescent staining of Raji cells using IL-4 Recombinant antibody (83894-1-RR)

    IF Staining of Raji using 83894-1-RR (same clone as 83894-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Raji cells using IL-4 antibody (83894-1-RR, Clone: 240794A8 ) at dilution of 1:400 and CoraLite®594-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-4). This data was developed using the same antibody clone with 83894-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83894-1-RR

    Affinity and Kinetic Characterization of 83894-1-RR

    Biolayer interferometry (BLl) kinetic assays of 83894-1-RR against Human IL-4 were performed. The affinity constant is 1.41 nM.

Geprüfte Anwendungen

Produktinformation

83894-1-PBS bindet in IF/ICC, Indirect ELISA IL-4 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen IL-4 fusion protein Eg0104
Vollständiger Name interleukin 4
Berechnetes Molekulargewicht 153 aa, 17 kDa
GenBank-ZugangsnummerBC070123
Gene symbol IL-4
Gene ID (NCBI) 3565
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IL4 is a cytokine produced by CD4+ T cells in response to helminthes and other extracellular parasites. It promotes the proliferation and differentiation of antigen presenting cells. IL4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival.