IL-4RA/CD124 Monoklonaler Antikörper

IL-4RA/CD124 Monoklonal Antikörper für Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1B4D10

Kat-Nr. : 67051-5-PBS

Synonyme

IL4R, IL 4R subunit alpha, IL 4R alpha, IL 4 receptor subunit alpha, IL 4 binding protein

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  Cytometric bead array standard curve of MP50242-3

  Cytometric bead array standard curve of MP50242-3, IL4R/IL-4RA/CD124 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67051-3-PBS. Detection antibody: 67051-5-PBS. Standard:Ag28411. Range: 0.195-100 ng/mL.

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Geprüfte Anwendungen

Produktinformation

67051-5-PBS bindet in Cytometric bead array, Indirect ELISA IL-4RA/CD124 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: IL-4RA/CD124 fusion protein Ag28411
• Vollständiger Name: interleukin 4 receptor
• Berechnetes Molekulargewicht: 90 kDa
• GenBank-Zugangsnummer: NM_000418
• Gene symbol: IL-4R
• Gene ID (NCBI): 3566
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IL-4 receptor alpha chain (IL-4RA), also known as CD124, is a transmembrane glycoprotein expressed on a wide variety of hematopoietic and non-hematopoietic cells. It is a receptor for both IL-4 and IL-13. IL-4RA can complex with the common gamma chain (IL-2R gamma or CD132) and utilizes JAK1 and JAK2 for signal transduction, while complexes of IL-4RA with IL-13RA1 subunit mediate signals via JAK2 and Tyk2. The IL-4 response is involved in promoting Th2 differentiation. The IL-4/IL-13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation.