ILT-3/LILRB4 Rekombinanter Antikörper

ILT-3/LILRB4 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

250356B3

Kat-Nr. : 98486-3-PBS

Synonyme

LILRB4, B4, CD85 antigen-like family member K, CD85k, ILT3

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  FC experiment of human PBMCs using 98486-3-RR (same clone as 98486-3-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ILT-3/LILRB4 Rabbit RecAb (98486-3-RR, Clone: 250356B3) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L).Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98486-3-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98486-3-RR (same clone as 98486-3-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human ILT-3/LILRB4 Rabbit RecAb (98486-3-RR, Clone: 250356B3) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98486-3-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98486-3-PBS bindet in FC ILT-3/LILRB4 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: ILT-3/LILRB4 fusion protein Eg1743
• Vollständiger Name: leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
• Berechnetes Molekulargewicht: 49kDa
• GenBank-Zugangsnummer: AAH26309.1
• Gene symbol: LILRB4
• Gene ID (NCBI): 11006
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

LILRB4 is an inhibitory receptor in the LILR family mainly expressed on normal and malignant human cells of myeloid origin. LILRB4 is activated and subsequently recruits adaptors to cytoplasmic immunoreceptor tyrosine inhibitory motifs to initiate different signaling cascades, thus playing an important role in physiological and pathological conditions, including autoimmune diseases, microbial infections, and cancers.