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IMPDH2 Rekombinanter Antikörper

IMPDH2 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251066H6

Kat-Nr. : 86346-3-PBS

Synonyme

EC:1.1.1.205, IMP dehydrogenase II, IMPD 2, IMPD2, IMPDH 2

Filter:
  • Western Blot (WB) analysis of various lysates using IMPDH2 Recombinant antibody (86346-3-RR)

    WB analysis using 86346-3-RR (same clone as 86346-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86346-3-RR (IMPDH2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86346-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86346-3-RR

    Affinity and Kinetic Characterization of 86346-3-RR

    Biolayer interferometry (BLl) kinetic assays of 86346-3-RR against Human IMPDH2 were performed. The affinity constant is 1.95 nM.

Geprüfte Anwendungen

Produktinformation

86346-3-PBS bindet in WB, Indirect ELISA IMPDH2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen IMPDH2 fusion protein Ag3632
Vollständiger Name IMP (inosine monophosphate) dehydrogenase 2
Berechnetes Molekulargewicht 514 aa, 56 kDa
Beobachtetes Molekulargewicht56 kDa
GenBank-ZugangsnummerBC012840
Gene symbol IMPDH2
Gene ID (NCBI) 3615
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IMPDH2, also named as IMPD2, belongs to the IMPDH/GMPR family. It is a rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors. IMPDH2 is a key enzyme in the purine nucleotide biosynthetic pathway and constitutes a pivotal biological target for immunosuppressant and antiviral drugs. (PMID:21181270)