ING2 Monoklonaler Antikörper

ING2 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2C3A7

Kat-Nr. : 66512-1-PBS

Synonyme

ING1L, ING1Lp, ING2, Inhibitor of growth protein 2, p32, p33ING2

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  WB analysis of HSC-T6 using 66512-1-Ig (same clone as 66512-1-PBS)

  HSC-T6 cells were subjected to SDS PAGE followed by western blot with 66512-1-Ig (ING2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66512-1-PBS in a different storage buffer formulation.

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  WB analysis of NIH/3T3 using 66512-1-Ig (same clone as 66512-1-PBS)

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 66512-1-Ig (ING2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66512-1-PBS in a different storage buffer formulation.

• 

  WB analysis of T-47D using 66512-1-Ig (same clone as 66512-1-PBS)

  T-47D cells were subjected to SDS PAGE followed by western blot with 66512-1-Ig (ING2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66512-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

66512-1-PBS bindet in WB, Indirect ELISA ING2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: ING2 fusion protein Ag19291
• Vollständiger Name: inhibitor of growth family, member 2
• Berechnetes Molekulargewicht: 280 aa, 33 kDa
• Beobachtetes Molekulargewicht: 33-35 kDa
• GenBank-Zugangsnummer: BC030128
• Gene symbol: ING2
• Gene ID (NCBI): 3622
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ING2, also named as ING1L, belongs to the ING family and contains a PHD-type zinc finger. As a candidate tumor suppressor, ING2 seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. It is a component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. Recent finding reported that ING2 regulates muscle differentiation by regulating chormatin remodeling program.