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ING2 Monoklonaler Antikörper

ING2 Monoklonal Antikörper für

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

Konjugation

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

2C3A7

Kat-Nr. : CL488-66512

Synonyme

p32, Inhibitor of growth protein 2, Inhibitor of growth 1-like protein, ING1Lp, ING1L

Geprüfte Anwendungen

Produktinformation

CL488-66512 bindet in ING2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen ING2 fusion protein Ag19291
Vollständiger Name inhibitor of growth family, member 2
Berechnetes Molekulargewicht 280 aa, 33 kDa
Beobachtetes Molekulargewicht 33-35 kDa
GenBank-ZugangsnummerBC030128
Gene symbol ING2
Gene ID (NCBI) 3622
Konjugation CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA
LagerungsbedingungenBei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ING2, also named as ING1L, belongs to the ING family and contains a PHD-type zinc finger. As a candidate tumor suppressor, ING2 seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. It is a component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. Recent finding reported that ING2 regulates muscle differentiation by regulating chormatin remodeling program.