INPP5E Monoklonaler Antikörper

INPP5E Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2B3D6

Kat-Nr. : 68602-1-PBS

Synonyme

INPP5E, PPI5PIV

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  WB analysis using 68602-1-Ig (same clone as 68602-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68602-1-Ig (INPP5E antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68602-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 68602-1-Ig (same clone as 68602-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68602-1-Ig (INPP5E antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68602-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HaCaT using 68602-1-Ig (same clone as 68602-1-PBS)

  HaCaT cells were subjected to SDS PAGE followed by western blot with 68602-1-Ig (INPP5E antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68602-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

68602-1-PBS bindet in WB, Indirect ELISA INPP5E und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: INPP5E fusion protein Ag11959
• Vollständiger Name: inositol polyphosphate-5-phosphatase, 72 kDa
• Berechnetes Molekulargewicht: 644 aa, 70 kDa
• Beobachtetes Molekulargewicht: 72 kDa
• GenBank-Zugangsnummer: BC028032
• Gene symbol: INPP5E
• Gene ID (NCBI): 56623
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

INPP5E(72 kDa inositol polyphosphate 5-phosphatase) converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns-P2.In mouse, highest protein expression was in brain, heart, and testis, with lower expression in thymus and lung, and very little expression in kidney, spleen, and liver(PMID:10764818). Defects in INPP5E are the cause of Joubert syndrome type 1 (JBTS1) and mental retardation-truncal obesity-retinal dystrophy-micropenis (MORMS)(PMID:19668215).