INSM2 Polyklonaler Antikörper

INSM2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33151-1-PBS

Synonyme

IA6, INSM Transcriptional Repressor 2 , Insulinoma-associated protein 2, Nbla106, Zinc finger protein IA-6

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  WB analysis using 33151-1-AP (same clone as 33151-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 33151-1-AP (INSM2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33151-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

33151-1-PBS bindet in WB, Indirect ELISA INSM2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: INSM2 fusion protein Ag38945
• Vollständiger Name: insulinoma-associated 2
• Berechnetes Molekulargewicht: 59kDa，566aa
• Beobachtetes Molekulargewicht: 68 kDa
• GenBank-Zugangsnummer: NM_032594.3
• Gene symbol: INSM2
• Gene ID (NCBI): 84684
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

INSM2 (Insulinoma-associated protein 2) is a zinc-finger protein belonging to the transcription factor family and has transcriptional repressive functions. It may exert growth-inhibitory or tumor-suppressive effects in hepatocytes and certain neurons. The primary function of INSM2 involves the regulation of gene expression, particularly the repression of insulin gene expression in non-pancreatic cells. Additionally, INSM2 is upregulated in neuroblastoma and is associated with poor prognosis. It promotes tumor development by affecting lipid metabolism through the regulation of the mTOR signaling pathway.